p53 antibody,Genetex,GTX128135

Host

Rabbit

Reactivity

Zebrafish

Application

WB

Conjugate

Unconjugated

Platform ID

BAB651323061

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Namep53 antibody
Cat. No.GTX128135
Gene ID (Entrez)30590
HostRabbit
IsotypeIgG
ReactivityZebrafish
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration1.47 mg/ml (Please refer to the vial label for the specific concentration.)
Targettp53
ImmunogenRecombinant protein encompassing a sequence within the N-terminus region of zebrafish p53. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,0.025% ProClin 300
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression.

Synonyms

tumor protein p53 , brp53 , drp53 , etID22686.5 , fb40d06 , p53 , wu:fb40d06 , zgc:111919

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