p57 Kip2 antibody [3E3],Genetex,GTX80412

Host

Mouse

Reactivity

Human

Application

WB ELISA

Conjugate

Unconjugated

Platform ID

BAB311396189

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Namep57 Kip2 antibody [3E3]
Cat. No.GTX80412
Gene ID (Entrez)1028
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ELISA
ClonalityMonoclonal
TargetCDKN1C
ImmunogenPurified recombinant fragment of human CDKN1C expressed in E. Coli.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Synonyms

cyclin dependent kinase inhibitor 1C , BWCR , BWS , KIP2 , WBS , p57 , p57Kip2

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