p70 S6K (phospho Thr229) antibody,Genetex,GTX25231

Host

Rabbit

Reactivity

Human, Rat

Application

WB ICC/IF

Conjugate

Unconjugated

Platform ID

BAB928435041

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Namep70 S6K (phospho Thr229) antibody
Cat. No.GTX25231
Gene ID (Entrez)6198
HostRabbit
IsotypeIgG
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetRPS6KB1
ImmunogenThe antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human p70-S6K that contains threonine 229. The sequence is conserved in rat.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS, 0.1% BSA, 50% Glycerol,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

Synonyms

ribosomal protein S6 kinase B1 , PS6K , S6K , S6K-beta-1 , S6K1 , STK14A , p70 S6KA , p70(S6K)-alpha , p70-S6K , p70-alpha

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