pan-PKC Rabbit pAb- ABclonal,ABclonal,A17922

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, ELISA

Platform ID

BAB948058031

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

Contact

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Product Specifications
Scientific Background

Specifications

Namepan-PKC Rabbit pAb- ABclonal
Cat. No.A17922
RRID#N/A
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationWB, IF/ICC, ELISA
Working DilutionsWB:1:500 - 1:2000 | IF/ICC:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight83kDa
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption.

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