phospho-IGF1R (Tyr1165 + Tyr1166) Polyclonal Antibody,Bioss,bs-5449R

Host

Rabbit

Reactivity

Mouse, Rat

Application

ELISA, FCM

Conjugate

Unconjugated

Platform ID

BAB059291969

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

Namephospho-IGF1R (Tyr1165 + Tyr1166) Polyclonal Antibody
Cat. No.bs-5449R
Accession NumberP08069
Gene ID (Entrez)3480
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ConjugationUnconjugated
ApplicationELISA, FCM
Working DilutionsELISA:1:500-1000 | FCM:1:20-100
ClonalityPolyclonal
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008].

Synonyms

IGF-1R Tyr1165/Tyr1166; IGF1R phospho Y1165+Y1166; IGF1R phospho Tyr1165+Tyr1166; p-IGF1R Tyr1165+Tyr1166; CD221; CD221 antigen; IGF 1 receptor; IGF 1R; IGF I receptor; IGF1R; IGFIR; IGFIRC; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; JTK13; MGC142170; MGC142172; IGF1 Receptor; IGF1R_HUMAN.

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