phospho-MLKL (Ser345) Recombinant Antibody, AbBy Fluor-680 Conjugated,Bioss,bsm-54104r-bf680-100ul

Host

Rabbit

Reactivity

Mouse

Application

WB

Conjugate

AbBy Fluor-680

Platform ID

BAB104770129

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

Namephospho-MLKL (Ser345) Recombinant Antibody, AbBy Fluor-680 Conjugated
Cat. No.bsm-54104r-bf680-100ul
Accession NumberQ9D2Y4
Gene ID (Entrez)74568
HostRabbit
IsotypeIgG
ReactivityMouse
ConjugationAbBy Fluor-680
ApplicationWB
Working DilutionsWB:1:300-5000
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Synonyms

Phospho-MLKL (S345); pMLKL Ser345; Mixed lineage kinase domain-like protein, Mlkl

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