sRANKL antibody [12A668],Genetex,GTX13582

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF IHC-P FCM ChIP assay

Conjugate

Unconjugated

Platform ID

BAB350111390

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NamesRANKL antibody [12A668]
Cat. No.GTX13582
Gene ID (Entrez)21943
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P FCM ChIP assay
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTnfsf11
ImmunogenA bacterially expressed fusion protein containing amino acid residues 1-317 of mouse TRANCE was used as immunogen.
PurityProtein G purified
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

Synonyms

tumor necrosis factor (ligand) superfamily, member 11 , Ly109l , ODF , OPGL , RANKL , Trance

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