Search results for 1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody
1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody, Abbexa, abx005129
PIKFYVE Antibody is a Rabbit Polyclonal antibody against PIKFYVE. Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKfyve also has protein kinase activity. PIKfyve regulates endomembrane homeostasis and plays a role in the biogenesis of endosome carrier vesicles from early endosomes. Mutations in this gene cause corneal fleck dystrophy (CFD); an autosomal dominant disorder characterized by numerous small white flecks present in all layers of the corneal stroma. Histologically, these flecks appear to be keratocytes distended with lipid and mucopolysaccharide filled intracytoplasmic vacuoles. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody, Abbexa, abx325728
PIKFYVE Antibody is a Rabbit Polyclonal against PIKFYVE.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody, Abbexa, abx457507
1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody is a Rabbit polyclonal antibody for the detection of Human 1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody, Abbexa, abx104545
Polyclonal Antibody to 1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody, Abbexa, abx212236
PIKFYVE Antibody is a Rabbit Polyclonal against PIKFYVE.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody, Abbexa, abx320614
PIKFYVE Antibody is a Rabbit Polyclonal against PIKFYVE.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody, Abbexa, abx326663
PIKFYVE Antibody is a Rabbit Polyclonal against PIKFYVE.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
1-Phosphatidylinositol 3-Phosphate 5-Kinase (PIKFYVE) Antibody, Abbexa, abx212235
PIKFYVE Antibody is a Rabbit Polyclonal against PIKFYVE.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
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