Search results for 107515

Ultra-LEAF™ Purified anti-mouse TCR γ/δ Antibody, TCR γ/δ, UC7-13D5, BioLegend, 107515

Additional reported applications (for the relevant formats) include: immunoprecipitation1,in vitrostimulation1,2,4. Although several papers have reportedin vivodepletion3, 5,6, another study found that the effect of the antibody could be the functional blocking of the TCR signaling, rather than cell depletion7. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos.107515 - 107520).Though clone UC7-13D5 has been used for the depletion of TCR γ/δ T cells in vivo3-5, there is a report suggesting that binding of clone UC7-13D5 to the γ/δ TCR leads to downregulation of the γ/δ TCR, making the γ/δ T cells undetectable although they are still present7.