Search results for 14-3-3 Protein Sigma (SFN) Antibody
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx115864
14-3-3 Protein Sigma Antibody is a Rabbit Polyclonal antibody against 14-3-3 Protein Sigma.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugation
Unconjugated
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx338920
SFN Antibody is a Rabbit Polyclonal against SFN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx030571
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx455152
14-3-3 Protein Sigma (SFN) Antibody is a Rabbit polyclonal antibody for the detection of Human 14-3-3 Protein Sigma (SFN).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx032680
SFN Antibody is a Rabbit Polyclonal antibody against SFN.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx218542
14-3-3 Protein Sigma (SFN) Antibody is a Rabbit Polyclonal antibody for the detection of SFN. 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms, denoted 14-3-3 b, g, e, z, h, q and s, comprise this family of signaling intermediates. 14-3-3 s, also known as SFN, stratifin, HME1 or YWHAS, is a secreted adaptor protein that is involved in regulating both general and specific signaling pathways. Expressed predominately in stratified squamous keratinising epithelium, 14-3-3 s is able to bind and modify the activity of a large number of proteins, such as KRT17 (Keratin 17), through recognition of a phosphothreonine or phosphoserine motif. When bound to Keratin 17, for example, 14-3-3 s acts to stimulate the Akt/mTOR signaling pathway by upregulating protein synthesis and cell growth. 14-3-3 s also functions to positively mediate IGF-I-induced cell cycle progression and can bind to a variety of translation initiation factors, thus controlling mitotic translation. In response to tumor growth, 14-3-3 s positively regulates the tumor suppressor p53 and increases the rate of p53-regulated inhibition of G2/M cell cycle progression. Multiple isoforms of 14-3-3 s exist due to alternative splicing events.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx100294
Polyclonal Antibody to 14-3-3 Protein Sigma (SFN).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx174650
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. 14-3-3 Protein Sigma (SFN) Antibody is a Mouse Monoclonal antibody against 14-3-3 Protein Sigma (SFN).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx000967
SFN Antibody is a Rabbit Polyclonal antibody against SFN. 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms, denoted 14-3-3 b, g, e, z, h, q and s, comprise this family of signaling intermediates. 14-3-3 s, also known as SFN, stratifin, HME1 or YWHAS, is a secreted adaptor protein that is involved in regulating both general and specific signaling pathways. Expressed predominately in stratified squamous keratinising epithelium, 14-3-3 s is able to bind and modify the activity of a large number of proteins, such as KRT17 (Keratin 17), through recognition of a phosphothreonine or phosphoserine motif. When bound to Keratin 17, for example, 14-3-3 s acts to stimulate the Akt/mTOR signaling pathway by upregulating protein synthesis and cell growth. 14-3-3 s also functions to positively mediate IGF-I-induced cell cycle progression and can bind to a variety of translation initiation factors, thus controlling mitotic translation. In response to tumor growth, 14-3-3 s positively regulates the tumor suppressor p53 and increases the rate of p53-regulated inhibition of G2/M cell cycle progression. Multiple isoforms of 14-3-3 s exist due to alternative splicing events.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
14-3-3 Protein Sigma (SFN) Antibody, Abbexa, abx325481
SFN Antibody is a Rabbit Polyclonal against SFN.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
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