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Brilliant Violet 570 anti-human CD16 Antibody  anti-CD16 - 3G8 Brand Logo
ID: BAB559111022

Brilliant Violet 570 anti-human CD16 Antibody anti-CD16 - 3G8, BioLegend, 302036

The 3G8 antibody clone blocks neutrophil phagocytosis and stimulates NK cell proliferation. It has been reported that this clone interacts with the FcγRIIa and FcγRIIIb receptors causing neutrophil activation and aggregation18.Due to this phenomenon staining in whole blood may cause a reduction in the number of granulocytes or alter their scatter profile.Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections6, immunoprecipitation3, stimulation of NK cell proliferation4, blocking of phagocytosis5, and blocking of immunoglobulin binding to FcγRIII7,8. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 302049, 302050, 302057, 302058).

Host

Mouse

Reactivity

Human, Cynomolgus, Rhesus

Applications

FC - Quality tested

Conjugation

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