Search results for 31815
NDRG1 (E2T5I) Rabbit Monoclonal Antibody#31815, Cell Signaling Technology (CST), 31815
NDRG1 (E2T5I) Rabbit Monoclonal Antibody recognizes endogenous levels of total NDRG1 protein.
Host
Rabbit
Reactivity
Mouse, Rat
Applications
Western Blotting: 1:1000 Immunofluorescence (Frozen): 1:200 - 1:800 Immunofluorescence (Immunocytochemistry): 1:200 - 1:800
Conjugation
MLH1 Primary Antibody, ProMab, 31815
The protein encoded by this gene can heterodimerize with mismatch repair endonuclease PMS2 to form MutL alpha, part of the DNA mismatch repair system. When MutL alpha is bound by MutS beta and some accessory proteins, the PMS2 subunit of MutL alpha introduces a single-strand break near DNA mismatches, providing an entry point for exonuclease degradation. The encoded protein is also involved in DNA damage signaling and can heterodimerize with DNA mismatch repair protein MLH3 to form MutL gamma, which is involved in meiosis. This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC).
Host
Reactivity
Applications
Conjugation
Please provide the required information below so that we can quickly source your products.