Search results for 31944
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TREM2 (E7O7Q) Rabbit Monoclonal Antibody (Alexa Fluor®488 Conjugate)#31944, Cell Signaling Technology (CST), 31944
TREM2 (E7O7Q) Rabbit Monoclonal Antibody (Alexa Fluor®488 Conjugate) recognizes endogenous levels of total TREM2 protein.
Host
Rabbit
Reactivity
Mouse
Applications
Flow Cytometry (Live): 1:50
Conjugation
CD43 Primary Antibody, ProMab, 31944
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome.
Host
Reactivity
Applications
Conjugation
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