Search results for Activin A Receptor Type IB Antibody
Activin A Receptor Type IB Antibody, Abbexa, abx033689
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with a cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. The gene for ACVR1B (activin A type IB receptor) is composed of 11 exons. Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants. The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Activin A Receptor Type IB Antibody (YA1989), MedChemexpress, HY-P82244
Activin A Receptor Type IB Antibody (YA1989) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Activin A Receptor Type IB.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, FC
Conjugation
Non-conjugated
Activin A Receptor Type IB Antibody (YA1989)(PBS only), MedChemexpress, HY-P82244A
Activin A Receptor Type IB Antibody (YA1989) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Activin A Receptor Type IB.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, FC
Conjugation
Non-conjugated
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