Search results for Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody, Abbexa, abx132816
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody is a Rabbit Polyclonal antibody for the detection of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4).
Host
Rabbit
Reactivity
Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody, Abbexa, abx241020
ACSL4 Antibody is a Rabbit Polyclonal against ACSL4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody, Abbexa, abx132815
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody is a Rabbit Polyclonal antibody for the detection of Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody, Abbexa, abx302763
ACSL4 Antibody is a Rabbit Polyclonal against ACSL4.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody, Abbexa, abx241847
ACSL4 Antibody is a Rabbit Polyclonal against ACSL4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody, Abbexa, abx005225
ACSL4 Antibody is a Rabbit Polyclonal antibody against ACSL4. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody, Abbexa, abx031624
Long chain acyl-CoA synthetase (LACS), or long chain fatty acid-CoA ligase (FACL), converts free long chain fatty acids into fatty acyl-CoA esters, key intermediates in the synthesis of complex lipids. The FACL4 gene encodes a form of LACS and is expressed in several tissues, including brain. FACL4 cDNA from brain encodes a gene product that shows preference for arachidonic acid as a substrate when expressed in mammalian cells.1 The sequence of the predicted 670-amino acid human protein is 97% identical to that of rat ACS4. FACL4 is highly expressed in adult human brain, especially in the cerebellum and hippocampus, similar to the mouse.2 A strong cytoplasmic staining was found in the Purkinje and granular cells of the cerebellum and the pyramidal layer of hippocampus, indicating that FACL4 is specifically expressed in neurons and not in glial cells. Two patients with Alport syndrome, elliptocytosis, and mental retardation carried a large deletion of the COL4A5 region that included FACL4.3 The absence of FACL4 might play a role in the development of mental retardation or other signs associated with Alport syndrome. Two point mutations, 1 missense and 1 splice site change, were reported in the FACL4 gene in 2 families with nonspecific mental retardation.2 Analysis of enzymatic activity in lymphoblastoid cell lines of affected individuals revealed low levels compared with normal cells, indicating that both mutations are null mutations.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody, Abbexa, abx028035
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody (HRP), Abbexa, abx306373
ACSL4 Antibody (HRP) is a Rabbit Polyclonal against ACSL4 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody (Biotin), Abbexa, abx306375
ACSL4 Antibody (Biotin) is a Rabbit Polyclonal against ACSL4 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
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