Search results for Adalimumab

Adalimumab Biosimilar – Anti-TNF alpha mAb – Research Grade, ProteoGenix, PX-TA1001

Description of Adalimumab Biosimilar - Anti-TNF alpha mAb - Research Grade General information about Adalimumab Adalimumab is a recombinant, human IgG1 monoclonal antibody directed against tumor necrosis factor-alpha (TNF-alpha), with immunomodulating activity. Upon administration, adalimumab binds to TNF-alpha, thereby preventing its binding to the p55 and p75 TNF cell surface receptors and inhibiting TNF-mediated immune responses. TNF-alpha, a pro-inflammatory cytokine, is upregulated in various autoimmune diseases.

Adalimumab, Kyinno, KB-1082

Adalimumab, Affinityimmuno, ab-131-adalimumab

Adalimumab, Abbexa, abx831078

Adalimumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting TNFSF2/TNF-alpha/TNFA, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor 2, 3. It was originally launched by Abbvie in the U. S. and approved in 2002 by the FDA 1. This drug is frequently known as Humira. It is produced by recombinant DNA technology using a mammalian cell expression system. This drug is available in a prefilled syringe form and convenient pen form for subcutaneous self-administered doses 1. A new biosimilar to adalimumab, named adalimumab-adaz, was approved by the FDA on October 31, 2018. This biosimilar is known as Hyrimoz, and is a trademark of Novartis AG 9.

Adalimumab Antibody, Abbexa, abx376585

Adalimumab Antibody is a rabbit polyclonal antibody for the detection of Adalimumab.

Human Anti-Adalimumab Antibody (Anti-Adalimumab) ELISA Kit, Abbexa, abx392468

Human Anti-Adalimumab Antibody (Anti-Adalimumab) ELISA Kit is an ELISA Kit against Anti-Adalimumab Antibody (Anti-Adalimumab).

Adalimumab ELISA Kit, ProteoGenix, KPTX127

Description of Adalimumab ELISA Kit Introduction to Adalimumab ELISA Kit The Adalimumab ELISA Kit is a highly sensitive and specific assay for the detection and quantification of Adalimumab, a monoclonal antibody used as a therapeutic target in the treatment of various autoimmune diseases. This kit is designed for use in research laboratories and clinical settings, providing a reliable and accurate method for measuring Adalimumab levels in biological samples. Structure of Adalimumab Adalimumab is a fully human monoclonal antibody that specifically targets and binds to tumor necrosis factor alpha (TNF-α), a pro-inflammatory cytokine involved in the pathogenesis of various autoimmune diseases such as rheumatoid arthritis, psoriasis, and Crohn’s disease. The antibody is composed of two heavy chains and two light chains, each containing a variable region that recognizes and binds to TNF-α, and a constant region that mediates effector functions such as complement activation and antibody-dependent cell-mediated cytotoxicity. Principle of the ELISA Kit The Adalimumab ELISA Kit is based on the principle of the enzyme-linked immunosorbent assay (ELISA), a widely used immunoassay technique for the detection and quantification of specific proteins in biological samples. The kit utilizes a microplate coated with a capture antibody that specifically binds to Adalimumab. The sample, along with a known amount of Adalimumab standards, is added to the microplate and allowed to incubate. Any Adalimumab present in the sample will bind to the capture antibody, while unbound proteins are washed away. A detection antibody, labeled with an enzyme, is then added to the microplate and binds to the captured Adalimumab. The amount of enzyme activity is directly proportional to the amount of Adalimumab present in the sample. Addition of a substrate for the enzyme produces a color change, which is measured and compared to the standard curve to determine the concentration of Adalimumab in the sample. Applications of Adalimumab ELISA Kit The Adalimumab ELISA Kit has a wide range of applications in both research and clinical settings. In research, it can be used to measure Adalimumab levels in biological samples from animal models, providing valuable information on the pharmacokinetics and pharmacodynamics of the antibody. It can also be used to study the mechanism of action of Adalimumab and its effects on TNF-α in various disease models. In clinical settings, the Adalimumab ELISA Kit is an important tool for monitoring the efficacy of Adalimumab therapy in patients with autoimmune diseases. By measuring the levels of Adalimumab in the blood, doctors can determine if the patient is responding to the treatment and adjust the dosage accordingly. It can also be used to detect the presence of anti-Adalimumab antibodies, which can reduce the effectiveness of the treatment and lead to treatment failure. Advantages of Adalimumab ELISA Kit The Adalimumab ELISA Kit offers several advantages over other methods of measuring Adalimumab levels, such as radioimmunoassay and enzyme-linked immunosorbent spot (ELISpot) assay. It is highly sensitive and specific, with a lower limit of detection of 0.1 ng/mL. It is also a cost-effective and high-throughput method, allowing for the simultaneous analysis of multiple samples. The results obtained from the kit are reliable and reproducible, making it a valuable tool for both research and clinical applications. Conclusion The Adalimumab ELISA Kit is a valuable tool for the detection and quantification of Adalimumab, a monoclonal antibody used as a therapeutic target in the treatment of autoimmune diseases. Its high sensitivity, specificity, and cost-effectiveness make it a preferred method for measuring Adalimumab levels in research and clinical settings. With the

Adalimumab ELISA Kit, Abbexa, abx395016

Adalimumab ELISA Kit is a quantitative ELISA kit for detection of Adalimumab.Adalimumab is a recombinant human IgG1 monoclonal antibody specific for Tumor Necrosis Factor-Alpha (TNF-a) and is used to treat rheumatic arthritis, intestinal disorders, dermatological diseases and cancer. Adalimumab specifically binds to TNF alpha and blocks its interaction with p55 and p75 cell surface TNF receptors and reduces the inflammation and subsequently improves the patient’s health. Drug level quantification can be important to adapt patient prescription or to switch to an alternative TNF inhibitor drug.

Anti-Adalimumab Polyclonal Antibody, AntibodySystem, PAB94401

Anti-Adalimumab ELISA Kit, Abbexa, abx395219

Anti-Adalimumab ELISA Kit is a quantitative ELISA kit for detection of antibodies against Adalimumab.Anti-Adalimumab is a recombinant human IgG1 monoclonal antibody specific for Tumor Necrosis Factor-Alpha (TNF-a) and is used to treat rheumatic arthritis, intestinal disorders, dermatological diseases and cancer. Anti-Adalimumab specifically binds to TNF alpha and blocks its interaction with p55 and p75 cell surface TNF receptors and reduces the inflammation and subsequently improves the patient’s health. Drug level quantification can be important to adapt patient prescription or to switch to an alternative TNF inhibitor drug.