Search results for Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx015766
This protein belongs to the aldehyde dehydrogenase family of proteins.Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations.Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme.A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme.The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer.This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx327692
ALDH2 Antibody is a Rabbit Polyclonal against ALDH2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx015767
This protein belongs to the aldehyde dehydrogenase family of proteins.Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations.Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme.A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme.The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer.This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx027970
ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx001138
ALDH2 Antibody is a Rabbit Polyclonal antibody against ALDH2. Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx431088
ALDH2 Antibody is a Goat Polyclonal antibody against ALDH2.
Host
Goat
Reactivity
Human, Mouse, Rat
Applications
P-ELISA, WB
Conjugation
Unconjugated
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx230291
ALDH2 Antibody is a Rabbit Polyclonal against ALDH2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx027971
ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx137544
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody is a Mouse Monoclonal antibody against Aldehyde Dehydrogenase, Mitochondrial (ALDH2).
Host
Mouse
Reactivity
Human
Applications
Conjugation
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody, Abbexa, abx402411
Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human, Mouse, Rat ALDH2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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