Search results for Antigen Peptide Transporter 1 (TAP1) Antibody
Antigen Peptide Transporter 1 (TAP1) Antibody, Abbexa, abx238499
TAP1 Antibody is a Rabbit Polyclonal against TAP1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated
Antigen Peptide Transporter 1 (TAP1) Antibody, Abbexa, abx433342
TAP1 Antibody is a Goat Polyclonal antibody against TAP1.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB
Conjugation
Unconjugated
Antigen Peptide Transporter 1 (TAP1) Antibody, Abbexa, abx455826
Antigen Peptide Transporter 1 (TAP1) Antibody is a Rabbit polyclonal antibody for the detection of Human Antigen Peptide Transporter 1 (TAP1).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Antigen Peptide Transporter 1 (TAP1) Antibody, Abbexa, abx025108
TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding. TAP is also inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association. Expression of TAP is down-regulated by human Epstein-barr virus vIL-10 protein, thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. TAP1 and TAP2 form a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP, inducible by interferon gamma, belongs to the ABC transporter family, MDR subfamily.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Antigen Peptide Transporter 1 (TAP1) Antibody, Abbexa, abx004748
TAP1 Antibody is a Rabbit Polyclonal antibody against TAP1. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Antigen Peptide Transporter 1 (TAP1) Antibody, Abbexa, abx320264
TAP1 Antibody is a Rabbit Polyclonal against TAP1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Antigen Peptide Transporter 1 (TAP1) Antibody, Abbexa, abx116251
Transporter 1, Atp-Binding Cassette, Sub-Family B (Mdr/Tap) Antibody is a Rabbit Polyclonal antibody against Transporter 1, Atp-Binding Cassette, Sub-Family B (Mdr/Tap).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Antigen Peptide Transporter 1 (TAP1) Antibody, Abbexa, abx171259
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Antigen Peptide Transporter 1 (TAP1) Antibody is a Mouse Monoclonal antibody against Antigen Peptide Transporter 1 (TAP1).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Antigen Peptide Transporter 1 (TAP1) Antibody, Abbexa, abx130661
Antigen Peptide Transporter 1 Antibody is a Rabbit Polyclonal against Antigen Peptide Transporter 1.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
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