Search results for Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx322923
BRCA1 Antibody is a Rabbit Polyclonal against BRCA1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx230942
BRCA1 Antibody is a Rabbit Polyclonal against BRCA1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx000600
BRCA1 Antibody is a Rabbit Polyclonal antibody against BRCA1. This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified.
Host
Rabbit
Reactivity
Human
Applications
IHC
Conjugation
Unconjugated
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx012846
Rabbit polyclonal antibody against BRCA1 protein. Immunogen region is C-terminal.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx015781
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor.The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC).This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes.This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination.Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers.Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene.Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described.A related pseudogene, which is also located on chromosome 17, has been identified.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx324469
BRCA1 Antibody is a Rabbit Polyclonal against BRCA1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx111256
Breast Cancer 1, Early Onset Antibody is a Rabbit Polyclonal antibody against Breast Cancer 1, Early Onset.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx125577
BRCA1 Antibody is a Rabbit Polyclonal against BRCA1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx210501
BRCA1 Antibody is a Rabbit Polyclonal against BRCA1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Breast Cancer Type 1 Susceptibility Protein (BRCA1) Antibody, Abbexa, abx125574
BRCA1 Antibody is a Rabbit Polyclonal against BRCA1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
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