Search results for CAMP-Dependent Protein Kinase Type I-Alpha Regulatory Subunit (PRKAR1A) Antibody
CAMP-Dependent Protein Kinase Type I-Alpha Regulatory Subunit (PRKAR1A) Antibody, Abbexa, abx236779
PRKAR1A Antibody is a Rabbit Polyclonal against PRKAR1A.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
CAMP-Dependent Protein Kinase Type I-Alpha Regulatory Subunit (PRKAR1A) Antibody, Abbexa, abx329382
PRKAR1A Antibody is a Rabbit Polyclonal against PRKAR1A.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
CAMP-Dependent Protein Kinase Type I-Alpha Regulatory Subunit (PRKAR1A) Antibody, Abbexa, abx114812
Protein Kinase, Camp-Dependent, Regulatory, Type I, Alpha (Tissue Specific Extinguisher 1) Antibody is a Rabbit Polyclonal antibody against Protein Kinase, Camp-Dependent, Regulatory, Type I, Alpha (Tissue Specific Extinguisher 1).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
CAMP-Dependent Protein Kinase Type I-Alpha Regulatory Subunit (PRKAR1A) Antibody, Abbexa, abx000892
PRKAR1A Antibody is a Rabbit Polyclonal antibody against PRKAR1A. cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Several alternatively spliced transcript variants encoding two different isoforms have been observed.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
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