Search results for CREB Regulated Transcription Coactivator 2 (CRTC2) Antibody
CREB Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx333835
CRTC2 Antibody is a Rabbit Polyclonal against CRTC2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
CREB-Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx432184
CRTC2 Antibody is a Goat Polyclonal antibody against CRTC2.
Host
Goat
Reactivity
Mouse, Rat
Applications
P-ELISA, WB
Conjugation
Unconjugated
CREB Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx111820
Creb Regulated Transcription Coactivator 2 Antibody is a Rabbit Polyclonal antibody against Creb Regulated Transcription Coactivator 2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
CREB-Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx432555
CRTC2 Antibody is a Goat Polyclonal antibody against CRTC2.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB
Conjugation
Unconjugated
CREB-Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx430461
CRTC2 Antibody is a Goat Polyclonal antibody against CRTC2.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB, IHC
Conjugation
Unconjugated
CREB Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx214343
CRTC2 Antibody is a Rabbit Polyclonal against CRTC2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
CREB-Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx432183
CRTC2 Antibody is a Goat Polyclonal antibody against CRTC2.
Host
Goat
Reactivity
Human, Rat
Applications
P-ELISA, WB, IF/ICC, FCM
Conjugation
Unconjugated
CREB-Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx027965
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
CREB-Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx027849
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
CREB-Regulated Transcription Coactivator 2 (CRTC2) Antibody, Abbexa, abx011916
the transducer of regulated CREB protein 2 (TORC2) is a cAMP responsive coactivator that, in concert with LKB1 and AMPK, controls glucose homeostasis in the liver. Under fasting conditions, cytoplasmic TORC2 is transported to the nucleus where it binds to CREB and stimulates gluconeogenisis. Re-feeding and the ensuing insulin response inhibits gluconeogenic gene expression by promoting the phosphorylation, cytoplasmic export and degradation of TORC2. TORC2 is phosphorylated by the kinase QIK which in turn is activated by phosphorylation at Ser358 by insulin-activated Akt2. Phosphorylated TORC2 is subsequently ubiquitinylated at Lys 628 and degraded by the 26S proteasome. TORC2 protein levels and activity are increased in diabetes owing to a block in TORC2 phosphorylation, implicating this pathway in the pathogenesis of diabetes. The CREB/TORC2 regulatory axis controls the normal pattern of germinal center (GC) B cell gene activation/repression that promotes B cell development and circumvents GC lymphomagenesis.
Host
Mouse
Reactivity
Human, Monkey
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
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