Search results for Cell Adhesion Molecule 1 (CADM1) Antibody
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx430138
CADM1 Antibody is a Goat Polyclonal antibody against CADM1.
Host
Goat
Reactivity
Mouse
Applications
P-ELISA, WB
Conjugation
Unconjugated
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx325695
CADM1 Antibody is a Rabbit Polyclonal against CADM1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx146655
Cell Adhesion Molecule 1 (CADM1) Antibody is a Rabbit Polyclonal antibody for the detection of CADM1. Mediates homophilic cell-cell adhesion in a Ca (2+) -independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca (2+) -independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx111516
Cell Adhesion Molecule 1 Antibody is a Rabbit Polyclonal antibody against Cell Adhesion Molecule 1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx013924
Rabbit polyclonal antibody against CADM1 protein. Immunogen region is C-terminal.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx171659
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Cell Adhesion Molecule 1 (CADM1) Antibody is a Mouse Monoclonal antibody against Cell Adhesion Molecule 1 (CADM1).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx231189
CADM1 Antibody is a Rabbit Polyclonal against CADM1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx001553
CADM1 Antibody is a Rabbit Polyclonal antibody against CADM1. Homologous to the poliovirus receptor (PVR/CD155), the Nectin immunoglobulin superfamily comprises four known isoforms, Nectin 1, 2, 3 and 4 (also designated TSLC1). TSLC1 is encoded by a tumor-suppressor gene in human non-small-cell lung cancer mapping to chromosome 11q23.2. The TSLC1 protein is an N-linked membrane glycoprotein that co-localizes with the Actin filament-binding protein, afadin, at cadherin-based adherens junctions in MDCKII epithelial cells. TSLC1 also interacts with the tumor-suppressor gene product DAL-1 (for differentially expressed in adenocarcinoma of the lung protein 1) to target Actin rearragement and cellular motility. TSLC1 may also form homodimers that function in homophilic, intracellular adhesion. TSLC1 expression is reduced or absent in a number of characterized cancer cell lines including A549. In prostate and breast cancer, as well as in pancreatic ductal adenocarcinoma, the TSLC1 promoter is commonly silenced by hypermethylation. Unlike other Nectins, which are more widely expressed, TSLC1 is mainly expressed in the placenta.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx128167
Cell Adhesion Molecule 1 Antibody is a Rabbit Polyclonal against Cell Adhesion Molecule 1.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Cell Adhesion Molecule 1 (CADM1) Antibody, Abbexa, abx431991
CADM1 Antibody is a Goat Polyclonal antibody against CADM1.
Host
Goat
Reactivity
Human, Mouse
Applications
P-ELISA, WB
Conjugation
Unconjugated
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