Search results for Checkpoint Kinase 2 (CHEK2) Antibody
Checkpoint Kinase 2 (CHEK2) Antibody, Abbexa, abx303397
CHEK2 Antibody is a Rabbit Polyclonal against CHEK2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Checkpoint Kinase 2 (CHEK2) Antibody, Abbexa, abx032373
CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Checkpoint Kinase 2 (CHEK2) Antibody (Biotin), Abbexa, abx303400
CHEK2 Antibody (Biotin) is a Rabbit Polyclonal against CHEK2 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Checkpoint Kinase 2 (CHEK2) Antibody (HRP), Abbexa, abx303398
CHEK2 Antibody (HRP) is a Rabbit Polyclonal against CHEK2 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Checkpoint Kinase 2 (CHEK2) Antibody (FITC), Abbexa, abx303399
CHEK2 Antibody (FITC) is a Rabbit Polyclonal against CHEK2 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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