Search results for Circadian locomoter output cycles protein kaput
Circadian Locomoter Output Cycles Protein Kaput (Clock) Antibody, Abbexa, abx013288
Rabbit polyclonal antibody against Clock protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody, Abbexa, abx328613
CLOCK Antibody is a Rabbit Polyclonal against CLOCK.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody, Abbexa, abx302600
CLOCK Antibody is a Rabbit Polyclonal against CLOCK.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody, Abbexa, abx004307
CLOCK Antibody is a Rabbit Polyclonal antibody against CLOCK. The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Polymorphisms in this gene may be associated with behavioral changes in certain populations and with obesity and metabolic syndrome. Alternative splicing results in multiple transcript variants.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody, Abbexa, abx376830
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody is a Rabbit polyclonal antibody for the detection of Human Circadian Locomoter Output Cycles Protein Kaput (CLOCK).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody, Abbexa, abx431169
CLOCK Antibody is a Goat Polyclonal antibody against CLOCK.
Host
Goat
Reactivity
Mouse, Rat
Applications
P-ELISA, WB
Conjugation
Unconjugated
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody, Abbexa, abx321582
CLOCK Antibody is a Rabbit Polyclonal against CLOCK.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody, Abbexa, abx171753
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody is a Mouse Monoclonal antibody against Circadian Locomoter Output Cycles Protein Kaput (CLOCK).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody, Abbexa, abx010471
BMAL1/2-CLOCK heterodimers activate E-box element (3'- CACGTG-5') transcription of a number of proteins of the circadian clock. Activates transcription of PER1 and PER2. This transcription is inhibited in a feedback loop by PER and CRY proteins. Component of the circadian clock oscillator which includes the CRY proteins, CLOCK or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Efficient DNA binding requires dimerization with another bHLH protein. Heterodimerization with BMAL1 is required for E-box-dependent transactivation, for CLOCK nuclear translocation and degradation, and, for phosphorylation of both CLOCK and BMAL1. Interaction with PER and CRY proteins requires translocation to the nucleus. Interaction of the CLOCK-BMAL1 heterodimer with PER or CRY inhibits transcription activation. Binds weakly ARNT and ARNT2 to form heterodimers which bind poorly to the E-box motif.
Host
Mouse
Reactivity
Human
Applications
ELISA, IF/ICC
Conjugation
Unconjugated
Circadian Locomoter Output Cycles Protein Kaput (CLOCK) Antibody, Abbexa, abx231769
CLOCK Antibody is a Rabbit Polyclonal against CLOCK.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC, IP
Conjugation
Unconjugated
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