Search results for Core-Binding Factor Subunit Beta (CBFB) Antibody
Core-Binding Factor Subunit Beta (CBFB) Antibody, Abbexa, abx004055
CBFB Antibody is a Rabbit Polyclonal antibody against CBFB. The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Core-Binding Factor Subunit Beta (CBFB) Antibody, Abbexa, abx307095
CBFB Antibody is a Rabbit Polyclonal against CBFB.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Core-Binding Factor Subunit Beta (CBFB) Antibody, Abbexa, abx329460
CBFB Antibody is a Rabbit Polyclonal against CBFB.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Core-Binding Factor Subunit Beta (CBFB) Antibody, Abbexa, abx013598
Rabbit polyclonal antibody against CBF beta protein. Immunogen region is N-terminal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Core-Binding Factor Subunit Beta (CBFB) Antibody, Abbexa, abx320094
CBFB Antibody is a Rabbit Polyclonal against CBFB.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Core-Binding Factor Subunit Beta (CBFB) Antibody, Abbexa, abx033053
CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Core-Binding Factor Subunit Beta (CBFB) Antibody (FITC), Abbexa, abx307097
CBFB Antibody (FITC) is a Rabbit Polyclonal against CBFB conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Core-Binding Factor Subunit Beta (CBFB) Antibody (Biotin), Abbexa, abx307098
CBFB Antibody (Biotin) is a Rabbit Polyclonal against CBFB conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Core-Binding Factor Subunit Beta (CBFB) Antibody (HRP), Abbexa, abx307096
CBFB Antibody (HRP) is a Rabbit Polyclonal against CBFB conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
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