Search results for Cullin 1 (CUL1) Antibody
Cullin 1 (CUL1) Antibody, Abbexa, abx028739
Core component of multiple cullin-RING-based SCF (SKP1-Cullin 1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF (BTRC) and SCF (FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF (FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF (BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5 and probably NFKB2. SCF (SKP2) directs ubiquination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. SCF (SKP2) directs ubiquination of ORC1L, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1. SCF (FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. SCF (FBXW2) directs ubiquitination of GCM1. SCF (FBXO32) directs ubiquitination of MYOD1. SCF (FBXO7) directs ubiquitination of BIRC2 and DLGAP5. SCF (FBXO33) directs ubiquitination of YBX1. SCF (FBXO11) does not seem to direct ubiquitination of TP53. SCF (BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF (Cyclin F) directs ubiquitination of CP110 (By similarity).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cullin 1 (CUL1) Antibody, Abbexa, abx130464
Cullin 1 Antibody is a Rabbit Polyclonal against Cullin 1.
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Cullin 1 (CUL1) Antibody, Abbexa, abx320103
Cullin 1 Antibody is a Rabbit Polyclonal against Cullin 1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Cullin 1 (CUL1) Antibody, Abbexa, abx326122
CUL1 Antibody is a Rabbit Polyclonal against CUL1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Cullin 1 (CUL1) Antibody, Abbexa, abx321517
Cullin 1 Antibody is a Rabbit Polyclonal against Cullin 1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cullin 1 (CUL1) Antibody, Abbexa, abx232073
Cullin 1 Antibody is a Rabbit Polyclonal against Cullin 1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IP
Conjugation
Unconjugated
Cullin 1 (CUL1) Antibody, Abbexa, abx001748
Cullin 1 Antibody is a Rabbit Polyclonal antibody against Cullin 1. Cullin 1 (cullin 1) is a protein-coding gene. Diseases associated with Cullin 1 include glomuvenous malformation. GO annotations related to this gene include ubiquitin protein ligase binding. An important paralog of this gene is CUL3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IF/ICC
Conjugation
Unconjugated
Cullin 1 (CUL1) Antibody, Abbexa, abx116818
Cullin 1 Antibody is a Rabbit Polyclonal antibody against Cullin 1 Antibody.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cullin 1 (CUL1) Antibody, Abbexa, abx037825
Rabbit Polyclonal against the Cullin 1 protein.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cullin 1 (CUL1) Antibody, Abbexa, abx013050
Rabbit polyclonal antibody against Cullin 1 protein. Immunogen region is C-terminal.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
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