Search results for Cyclin T1 (CCNT1) Antibody
Cyclin-T1 (CCNT1) Antibody, Abbexa, abx001674
CCNT1 Antibody is a Rabbit Polyclonal antibody against CCNT1. This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Cyclin T1 (CCNT1) Antibody, Abbexa, abx232132
Cyclin T1 Antibody is a Rabbit Polyclonal against Cyclin T1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Cyclin-T1 (CCNT1) Antibody, Abbexa, abx025835
CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Cyclin T1 (CCNT1) Antibody, Abbexa, abx211600
CCNT1 Antibody is a Rabbit Polyclonal against CCNT1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
Cyclin-T1 (CCNT1) Antibody, Abbexa, abx301807
CCNT1 Antibody is a Rabbit Polyclonal against CCNT1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Cyclin T1 (CCNT1) Antibody, Abbexa, abx212960
CCNT1 Antibody is a Rabbit Polyclonal against CCNT1.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
Cyclin T1 (CCNT1) Antibody (FITC), Abbexa, abx315217
CCNT1 Antibody (FITC) is a Rabbit Polyclonal against CCNT1 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Cyclin T1 (CCNT1) Antibody (HRP), Abbexa, abx315216
CCNT1 Antibody (HRP) is a Rabbit Polyclonal against CCNT1 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Cyclin T1 (CCNT1) Antibody (Biotin), Abbexa, abx315218
CCNT1 Antibody (Biotin) is a Rabbit Polyclonal against CCNT1 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
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