Search results for Cyclin-dependent kinase 1
Cyclin-Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx159423
CDK1 Antibody is a Mouse Monoclonal against CDK1.
Host
Mouse
Reactivity
Human, Mouse, Rat, Dog
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Cyclin-Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx011637
The cell division control protein cdc2, also known as cyclin-dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S-phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2 delta T is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Cyclin Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx102538
Polyclonal Antibody to CDK1 (CDK1).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Cyclin-Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx028463
CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, FCM
Conjugation
Unconjugated
Cyclin Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx171975
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Cyclin Dependent Kinase 1 (CDK1) Antibody is a Mouse Monoclonal antibody against Cyclin Dependent Kinase 1 (CDK1).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Cyclin-Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx015728
The cell division control protein cdc2, also known as cyclin-dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S-phase and mitosis.Cdc2 exists as a complex with both cyclin A and cyclin B.The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition.Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161.However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14.Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase.The isoform CDC2deltaT is found in breast cancer tissues.Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IF/ICC, FCM
Conjugation
Unconjugated
Cyclin-Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx327043
CDK1 Antibody is a Rabbit Polyclonal against CDK1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Cyclin Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx139346
CDK1 Antibody is a Mouse Monoclonal against CDK1.
Host
Mouse
Reactivity
Human, Monkey, Cow
Applications
WB, IHC, IF/ICC, IP
Conjugation
Unconjugated
Cyclin Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx015811
The protein encoded by this gene is a member of the Ser/Thr protein kinase family.This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle.Mitotic cyclins stably associate with this protein and function as regulatory subunits.The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle.The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Cyclin-Dependent Kinase 1 (CDK1) Antibody, Abbexa, abx013362
Rabbit polyclonal antibody against CDC2 protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
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