Search results for Death Domain Associated Protein / DAP6 (DAXX) Antibody
Death Domain Associated Protein / DAP6 (DAXX) Antibody, Abbexa, abx010630
Daxx is a transcriptional co-regulatory protein. Proposed to mediate activation of the JNK pathway and apoptosis via ASK1 in response to signaling from FAS and TGF beta R2. Glucose deprivation activates the ASK1-SEK1-JNK1-HIPK1 pathway, relocalizing Daxx from the nucleus to the cytoplasm, where Daxx binds to ASK1, and subsequently leads to ASK1 oligomerization. Interaction with HSP27 may prevent interaction with TGF beta R2 and ASK1 and block DAXX-mediated apoptosis. Seems to act as a transcriptional co- repressor and inhibits PAX3 and ETS1 through direct protein- protein interaction. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Two alternatively spliced isoforms have been described.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IF/ICC, FCM
Conjugation
Unconjugated
Death Domain Associated Protein / DAP6 (DAXX) Antibody, Abbexa, abx232249
DAXX Antibody is a Rabbit Polyclonal against DAXX.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Death Domain Associated Protein / DAP6 (Daxx) Antibody, Abbexa, abx139393
Daxx Antibody is a Mouse Monoclonal against Daxx.
Host
Mouse
Reactivity
Human
Applications
WB, IF/ICC, IP
Conjugation
Unconjugated
Death Domain Associated Protein / DAP6 (Daxx) Antibody, Abbexa, abx139394
Daxx Antibody is a Mouse Monoclonal against Daxx.
Host
Mouse
Reactivity
Human
Applications
WB, IF/ICC
Conjugation
Unconjugated
Please provide the required information below so that we can quickly source your products.