Search results for Deoxyuridine 5'-Triphosphate Nucleotidohydrolase, Mitochondrial (DUT) Antibody
Deoxyuridine 5'-Triphosphate Nucleotidohydrolase, Mitochondrial (DUT) Antibody, Abbexa, abx455177
Deoxyuridine 5'-Triphosphate Nucleotidohydrolase, Mitochondrial (DUT) Antibody is a Rabbit polyclonal antibody for the detection of Human Deoxyuridine 5'-Triphosphate Nucleotidohydrolase, Mitochondrial (DUT).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Deoxyuridine 5'-Triphosphate Nucleotidohydrolase, Mitochondrial (DUT) Antibody, Abbexa, abx232572
DUT Antibody is a Rabbit Polyclonal against DUT.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Deoxyuridine 5'-Triphosphate Nucleotidohydrolase, Mitochondrial (DUT) Antibody, Abbexa, abx002131
DUT Antibody is a Rabbit Polyclonal antibody against DUT. This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Deoxyuridine 5'-Triphosphate Nucleotidohydrolase, Mitochondrial (DUT) Antibody, Abbexa, abx242484
DUT Antibody is a Rabbit Polyclonal against DUT.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Deoxyuridine 5'-Triphosphate Nucleotidohydrolase, Mitochondrial (DUT) Antibody, Abbexa, abx027875
This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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