Search results for Dihydrolipoyl Transacetylase (DLAT) Antibody
Dihydrolipoyl Transacetylase (DLAT) Antibody, Abbexa, abx112074
Dihydrolipoamide S-Acetyltransferase Antibody is a Rabbit Polyclonal antibody against Dihydrolipoamide S-Acetyltransferase.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Dihydrolipoyl Transacetylase (DLAT) Antibody, Abbexa, abx004805
DLAT Antibody is a Rabbit Polyclonal antibody against DLAT. This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Dihydrolipoyl Transacetylase (DLAT) Antibody, Abbexa, abx102842
Polyclonal Antibody to Dihydrolipoyl Transacetylase (DLAT).
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Dihydrolipoyl Transacetylase (DLAT) Antibody, Abbexa, abx232404
DLAT Antibody is a Rabbit Polyclonal against DLAT.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC, IP
Conjugation
Unconjugated
Dihydrolipoyl Transacetylase (DLAT) Antibody, Abbexa, abx338594
DLAT Antibody is a Rabbit Polyclonal against DLAT.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IP
Conjugation
Unconjugated
Dihydrolipoyl Transacetylase (DLAT) Antibody, Abbexa, abx242023
DLAT Antibody is a Rabbit Polyclonal against DLAT.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Dihydrolipoyl Transacetylase (DLAT) Antibody, Abbexa, abx102841
Polyclonal Antibody to Dihydrolipoyl Transacetylase (DLAT).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Dihydrolipoyl Transacetylase (DLAT) Antibody, Abbexa, abx214024
DLAT Antibody is a Rabbit Polyclonal against DLAT.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Dihydrolipoyl Transacetylase (DLAT) Antibody, Abbexa, abx032483
DLAT encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
Dihydrolipoyl Transacetylase (DLAT) Antibody (HRP), Abbexa, abx335334
DLAT Antibody (HRP) is a Rabbit Polyclonal against DLAT.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
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