Search results for Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody
Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody, Abbexa, abx025427
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq]. This antibody is supplied as crude ascites.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody, Abbexa, abx010632
DDR2 (discoidin domain receptor family, member 2) is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody, Abbexa, abx135978
DDR2 Antibody is a Rabbit Polyclonal against DDR2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody, Abbexa, abx318254
DDR2 Antibody is a Rabbit Polyclonal against DDR2.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody (FITC), Abbexa, abx316256
DDR2 Antibody (FITC) is a Rabbit Polyclonal against DDR2 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody (Biotin), Abbexa, abx316257
DDR2 Antibody (Biotin) is a Rabbit Polyclonal against DDR2 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Discoidin Domain Receptor Tyrosine Kinase 2 (DDR2) Antibody (HRP), Abbexa, abx316255
DDR2 Antibody (HRP) is a Rabbit Polyclonal against DDR2 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
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