Search results for Docking Protein 4 (DOK4) Antibody
Docking Protein 4 (DOK4) Antibody, Abbexa, abx112150
Docking Protein 4 Antibody is a Rabbit Polyclonal antibody against Docking Protein 4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Docking Protein 4 (DOK4) Antibody, Abbexa, abx326161
DOK4 Antibody is a Rabbit Polyclonal against DOK4.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Docking Protein 4 (DOK4) Antibody, Abbexa, abx212224
DOK4 Antibody is a Rabbit Polyclonal against DOK4.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
Docking Protein 4 (DOK4) Antibody, Abbexa, abx013720
Rabbit polyclonal antibody against DOK4 protein. Immunogen region is N-terminal.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Docking Protein 4 (DOK4) Antibody, Abbexa, abx000611
DOK4 Antibody is a Rabbit Polyclonal antibody against DOK4. The downstream of kinase family (Dok-1-7) are members of a class of docking proteins that interact with receptor tyrosine kinases and, via this interaction, mediate biological responses within the body. Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Docking Protein 4 (DOK4) Antibody, Abbexa, abx212225
DOK4 Antibody is a Rabbit Polyclonal against DOK4.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
Docking Protein 4 (DOK4) Antibody, Abbexa, abx033623
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Docking Protein 4 (DOK4) Antibody, Abbexa, abx232503
DOK4 Antibody is a Rabbit Polyclonal against DOK4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
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