Search results for Dupilumab

Dupilumab Biosimilar – Anti-IL4R, CD124 mAb – Research Grade, ProteoGenix, PX-TA1308

Description of Dupilumab Biosimilar - Anti-IL4R, CD124 mAb - Research Grade General information on Anti-IL4R/CD124[Homo sapiens] (Dupilumab) Monoclonal Antibody Dupilumab is a human monoclonal antibody of isotype IgG4 that targets the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. Dupilumab inhibits the signaling pathway of interleukins, that induce inflammatory and immunological reactions in several atopic or allergic conditions, such as eczema, allergic reaction, and rhinosinusitis.Dupilumab has been marketed under the trade name Dupixent. It has been also investigated for the treatment of diseases driven by allergic reactions or type 2 inflammation, such as pediatric atopic dermatitis, eosinophilic esophagitis, and chronic obstructive pulmonary disease.

Dupilumab, Kyinno, KB-1309

Dupilumab, Abbexa, abx831266

Dupilumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting IL4R/CD124, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis.

Dupilumab Antibody, Abbexa, abx376597

Dupilumab Antibody is a rabbit polyclonal antibody for the detection of Dupilumab.

Human Anti-Dupilumab Antibody (Anti-Dupilumab) ELISA Kit, Abbexa, abx392502

Human Anti-Dupilumab Antibody (Anti-Dupilumab) ELISA Kit is an ELISA Kit against Anti-Dupilumab Antibody (Anti-Dupilumab).

Dupilumab ELISA Kit, ProteoGenix, KPTX211

Description of Dupilumab ELISA Kit The Structure of Dupilumab ELISA Kit Dupilumab ELISA Kit is a highly sensitive and specific diagnostic tool used for the detection and quantification of Dupilumab, a monoclonal antibody used in the treatment of various inflammatory diseases. The kit is designed to measure the levels of Dupilumab in various biological samples such as serum, plasma, and cell culture supernatants. The kit is composed of a set of pre-coated microtiter wells, which are coated with a highly specific monoclonal antibody against Dupilumab. This antibody is immobilized on the surface of the microtiter wells and serves as the capture antibody for Dupilumab. The kit also includes a biotinylated detection antibody, which is specific for another epitope on Dupilumab. This detection antibody is labeled with biotin and is used to detect the captured Dupilumab. In addition, the kit contains streptavidin-conjugated horseradish peroxidase (HRP), which binds to the biotinylated detection antibody. This HRP conjugate catalyzes a colorimetric reaction in the presence of a substrate, resulting in the development of a color signal that is directly proportional to the amount of Dupilumab present in the sample. The Activity of Dupilumab ELISA Kit Dupilumab ELISA Kit is a highly sensitive and specific assay that provides accurate and reliable results for the quantification of Dupilumab. The kit has been optimized to have a low limit of detection (LOD) and a wide dynamic range, making it suitable for the detection of Dupilumab in a variety of biological samples. The kit utilizes a sandwich ELISA format, which ensures high specificity and sensitivity. The capture antibody and the detection antibody used in the kit are highly specific for different epitopes on Dupilumab, ensuring that only the target molecule is detected. This eliminates the possibility of any cross-reactivity with other proteins or molecules present in the sample. The colorimetric reaction catalyzed by the HRP conjugate is highly sensitive and produces a strong color signal, making it easy to detect and quantify even low levels of Dupilumab in the sample. The kit also has a high reproducibility, with low intra- and inter-assay variability, ensuring consistent results every time. The Application of Dupilumab ELISA Kit Dupilumab ELISA Kit has a wide range of applications in the field of drug development and clinical research. It is primarily used for the quantification of Dupilumab in biological samples, making it an essential tool for monitoring the efficacy of Dupilumab therapy in patients with inflammatory diseases such as atopic dermatitis and asthma. The kit can also be used for the detection and quantification of Dupilumab in cell culture supernatants, which is crucial for the development and optimization of cell-based assays. It can also be used to measure the levels of Dupilumab in animal models, providing valuable insights into the pharmacokinetics and pharmacodynamics of the drug. Furthermore, Dupilumab ELISA Kit can be used in preclinical and clinical studies to evaluate the pharmacokinetics and immunogenicity of Dupilumab, which is essential for the development and approval of new therapeutics. It can also be used to screen potential therapeutic candidates that target Dupilumab, making it a valuable tool in drug discovery and development. Conclusion Dupilumab ELISA Kit is a highly sensitive and specific diagnostic tool that is essential for the detection and quantification of Dupilumab. The kit’s unique sandwich ELISA format, along with its optimized components, ensures high specificity and sensitivity, making it suitable for a variety of applications in drug development and clinical research. With its accurate and reliable results, Dupilumab ELISA Kit plays a crucial role

Dupilumab ELISA Kit, Abbexa, abx395221

Dupilumab ELISA Kit is a quantitative ELISA kit for detection of Dupilumab. Dupilumab is a human immunoglobulin G4 (IgG4) antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%. A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%.

Dupilumab ELISA Kit, Abbexa, abx395100

Dupilumab ELISA Kit is a quantitative ELISA kit for detection of Dupilumab.Dupilumab is a human immunoglobulin G4 (IgG4) antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%. A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%.

Anti-Dupilumab Polyclonal Antibody, AntibodySystem, PAD62601

Dupilumab Biosimilar - Research Grade, ichor.bio, ICH5062

Detects human IL-4R alpha. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Dupilumab.