Search results for Dynamin 1 Like Protein (DNM1L) Antibody
Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx015842
The protein encoded by this gene is a member of the dynamin superfamily of GTPases.Members of the dynamin-related subfamily, including the S.cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains.This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm.The gene has 3 alternatively spliced transcripts encoding different isoforms.These transcripts are alternatively polyadenylated.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx122714
Rabbit Polyclonal against the DNM1L protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx303650
DNM1L Antibody is a Rabbit Polyclonal against DNM1L.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Dynamin-1-Like Protein (DNM1L) Antibody, Abbexa, abx376716
Dynamin-1-Like Protein (DNM1L) Antibody is a Rabbit polyclonal antibody for the detection of Human Dynamin-1-Like Protein (DNM1L).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Dynamin-1-Like Protein (DNM1L) Antibody, Abbexa, abx013015
Dynamin-1-Like Protein (DNM1L) antibody is a Rabbit polyclonal against Dynamin-1-Like Protein (DNM1L).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB
Conjugation
Unconjugated
Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx126887
DNM1L Antibody is a Rabbit Polyclonal against DNM1L.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF/ICC
Conjugation
Unconjugated
Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx224029
DNM1L Antibody is a Mouse Monoclonal against DNM1L.
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC, FCM
Conjugation
Dynamin 1 Like Protein (DNM1L) Antibody, Abbexa, abx002022
DNM1L Antibody is a Rabbit Polyclonal antibody against DNM1L. Dynamin-related protein 1 (DNM1L) is a member of the dynamin superfamily of GTPases. Members of this family have diverse cellular functions including vesicle scission, organelle fission, viral resistance, and intracellular trafficking (reviewed in 1). DNM1L affects mitochondrial morphology and is important in mitochondrial and peroxisomal fission in mammalian cells (2-5). The yeast ortholog of DNM1L clusters into a spiral-shaped structure on the mitochondrial membrane at the site of fission (reviewed in 6), and this structure is likely conserved in mammalian cells (3). The division of the mitochondria, which is required for apoptosis, as well as normal cell growth and development is controlled, in part, by the phosphorylation of DNM1L at Ser616 by Cdk1/cyclin B and at Ser637 by protein kinase A (PKA) (reviewed in 6). When phosphorylated at Ser616, DNM1L stimulates mitochondrial fission during mitosis. Conversely, fission is inhibited when DNM1L is phosphorylated at Ser637 (reviewed in 6). Dephosphorylation at Ser637 by calcineurin reverses this inhibition (7). In addition to phosphorylation, sumoylation of DNM1L is also an enhancer of mitochondrial fission (8). Balancing fission and fusion events is essential for proper mitochondrial function. Research studies have demonstrated mitochondrial defects in a variety of neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease (reviewed in 6).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Dynamin 1 Like Protein (DNM1L) Antibody (Biotin), Abbexa, abx303653
DNM1L Antibody (Biotin) is a Rabbit Polyclonal against DNM1L conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Dynamin 1 Like Protein (DNM1L) Antibody (FITC), Abbexa, abx303652
DNM1L Antibody (FITC) is a Rabbit Polyclonal against DNM1L conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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