Search results for Enfortumab

Enfortumab Biosimilar – Anti-PVRL4 mAb – Research Grade, ProteoGenix, PX-TA1333

Description of Enfortumab Biosimilar - Anti-PVRL4 mAb - Research Grade General information on Anti-PVRL4[Homo sapiens] (Enfortumab) Monoclonal Antibody Enfortumab is a human monoclonal antibody that targets Nectin-4. It has been used as an antibody drug conjugate (ADC), Enfortumab vedotin to treat patients with advanced, treatment-resistant urothelial cancers.It has been marketed under the tradename Padcev.

Enfortumab, Kyinno, KB-1185

Enfortumab, Abbexa, abx831292

Enfortumab is a monoclonal antibody biosimilar expressed in CHO cells, targeting PVRL4, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications. Enfortumab vedotin is an antibody-drug conjugate used in the treatment of patients with advanced, treatment-resistant urothelial cancers. It is comprised of a fully human monoclonal antibody targeted against Nectin-4 and a microtubule-disrupting chemotherapeutic agent, monomethyl auristatin E (MMAE), joined by a protease-cleavable link. It is similar to brentuximab vedotin, another antibody conjugated with MMAE that targets CD-30 instead of Nectin-4. The clinical development of enfortumab vedotin was the result of a collaboration between Astellas Pharma and Seattle Genetics and it was first approved for use in the United States in December 2019 under the brand name PadcevTM.

Human Anti-Enfortumab Antibody (Anti-Enfortumab) ELISA Kit, Abbexa, abx392505

Human Anti-Enfortumab Antibody (Anti-Enfortumab) ELISA Kit is an ELISA Kit against Anti-Enfortumab Antibody (Anti-Enfortumab).

Enfortumab ELISA Kit, ProteoGenix, KPTX272

Description of Enfortumab ELISA Kit Introduction to Enfortumab ELISA Kit Enfortumab ELISA Kit is a highly sensitive and specific assay designed for the detection and quantification of Enfortumab, a novel antibody therapy targeting Nectin-4, a cell adhesion molecule overexpressed in many solid tumors. This advanced ELISA kit is a valuable tool for researchers and clinicians to study the structure, activity, and application of Enfortumab in various cancer types. Structure of Enfortumab Enfortumab is a humanized monoclonal antibody consisting of two heavy chains and two light chains. The heavy chains are composed of four constant domains (CH1, CH2, CH3, and CH4) and one variable domain (VH), while the light chains consist of one constant domain (CL) and one variable domain (VL). The variable domains of both heavy and light chains are responsible for binding to the Nectin-4 protein. Activity of Enfortumab Enfortumab acts as an immune checkpoint inhibitor by blocking the interaction between Nectin-4 and its receptor, leading to the activation of immune cells and subsequent destruction of tumor cells. This antibody also induces antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC) to eliminate cancer cells. In addition, Enfortumab has been shown to inhibit tumor growth and metastasis in preclinical studies. Application of Enfortumab ELISA Kit The Enfortumab ELISA Kit is a valuable tool for researchers and clinicians to study the pharmacokinetics and pharmacodynamics of Enfortumab in various cancer types. It can also be used to monitor the levels of Enfortumab in patient serum or plasma, which can provide valuable information for dose optimization and treatment response evaluation. Additionally, this ELISA kit can be used to measure the levels of Nectin-4 in tumor tissue, which can help in patient selection for Enfortumab therapy. Advantages of Enfortumab ELISA Kit The Enfortumab ELISA Kit offers several advantages over other methods of Enfortumab detection. Firstly, it provides high sensitivity and specificity, allowing for accurate quantification of Enfortumab even at low levels. Secondly, it is a cost-effective and time-efficient assay, making it suitable for high-throughput screening. Thirdly, it can be used with various sample types, including serum, plasma, and tissue lysates, making it a versatile tool for Enfortumab research. Conclusion In summary, Enfortumab ELISA Kit is a highly sensitive and specific assay designed for the detection and quantification of Enfortumab, a novel antibody therapy targeting Nectin-4. Its advanced technology and multiple applications make it a valuable tool for researchers and clinicians to study the structure, activity, and application of Enfortumab in various cancer types. With the increasing use of Enfortumab in clinical practice, this ELISA kit will continue to play a crucial role in monitoring treatment response and optimizing Enfortumab therapy for cancer patients.

Enfortumab ELISA Kit, Abbexa, abx395161

Enfortumab ELISA Kit is a quantitative ELISA kit for detection of Enfortumab.

Enfortumab Biosimilar - Research Grade, ichor.bio, ICH5070

Detects human Nectin-4. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Enfortumab

Enfortumab Vedotin Biosimilar - Research Grade, ichor.bio, ICH5070V