Search results for Enhancer of Polycomb Homolog 1 (EPC1) Antibody
Enhancer of Polycomb Homolog 1 (EPC1) Antibody, Abbexa, abx004449
EPC1 Antibody is a Rabbit Polyclonal antibody against EPC1. This gene encodes a member of the polycomb group (PcG) family. The encoded protein is a component of the NuA4 histone acetyltransferase complex and can act as both a transcriptional activator and repressor. The encoded protein has been linked to apoptosis, DNA repair, skeletal muscle differentiation, gene silencing, and adult T-cell leukemia/lymphoma. Alternative splicing results in multiple transcript variants.
Host
Rabbit
Reactivity
Human, Mouse
Applications
IF/ICC
Conjugation
Unconjugated
Enhancer of Polycomb Homolog 1 (EPC1) Antibody, Abbexa, abx034869
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
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