Search results for Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx146917
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody is a Rabbit Polyclonal antibody for the detection of DDR1. Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx421774
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody is a Mouse Monoclonal antibody for the detection of Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) in Human samples.
Host
Mouse
Reactivity
Human
Applications
ELISA, FCM
Conjugation
Unconjugated
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx421189
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody is a Mouse Monoclonal antibody for the detection of Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) in Human samples.
Host
Mouse
Reactivity
Human
Applications
FCM
Conjugation
Unconjugated
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx240041
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody is a Rabbit Polyclonal antibody for the detection of DDR1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx011452
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Three isoforms of this gene are generated by alternative splicing. [PROW].
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx455890
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody is a Rabbit polyclonal antibody for the detection of Human Epithelial Discoidin Domain-Containing Receptor 1 (DDR1).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx013005
Rabbit polyclonal antibody against DDR1 protein. Immunogen region is C-terminal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
Conjugation
Unconjugated
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx323695
DDR1 Antibody is a Rabbit Polyclonal against DDR1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx421771
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody is a Mouse Monoclonal antibody for the detection of Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) in Human samples.
Host
Mouse
Reactivity
Human
Applications
ELISA, FCM
Conjugation
Unconjugated
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody, Abbexa, abx033583
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. The gene is located on chromosome 6p21.3 in proximity to several HLA class I genes.
Host
Rabbit
Reactivity
Human, Rat
Applications
ELISA, WB, IHC, FCM
Conjugation
Unconjugated
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