Search results for Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody, Abbexa, abx010311
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody is a Rabbit Polyclonal antibody for the detection of 4EBP1. Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody, Abbexa, abx230006
4EBP1 Antibody is a Mouse Monoclonal against 4EBP1.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody, Abbexa, abx010313
4E-BP1 (eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I,which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while (24kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody, Abbexa, abx015717
4E-BP1 (eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I,which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa).Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1.Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while (24kDa), the phosphorylated form will not.Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64.Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody, Abbexa, abx012767
Rabbit polyclonal antibody against 4E-BP1 protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody, Abbexa, abx015716
4E-BP1 (eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I,which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa).Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1.Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while (24kDa), the phosphorylated form will not.Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64.Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody, Abbexa, abx010312
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody is a Rabbit Polyclonal antibody for the detection of 4EBP1. Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody, Abbexa, abx012960
Rabbit polyclonal antibody against 4E-BP1 protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody, Abbexa, abx012768
Rabbit polyclonal antibody against 4E-BP1 protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
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