Search results for Exosome Component 2 (EXOSC2) Antibody
Exosome Component 2 (EXOSC2) Antibody, Abbexa, abx034983
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Exosome Component 2 (EXOSC2) Antibody, Abbexa, abx125830
EXOSC2 Antibody is a Rabbit Polyclonal against EXOSC2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Exosome Component 2 (EXOSC2) Antibody, Abbexa, abx176346
Exosome Component 2 (EXOSC2) Antibody is a Rabbit Polyclonal antibody against Exosome Component 2 (EXOSC2).
Host
Rabbit
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Exosome Component 2 (EXOSC2) Antibody, Abbexa, abx172308
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Exosome Component 2 (EXOSC2) Antibody is a Mouse Monoclonal antibody against Exosome Component 2 (EXOSC2).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Exosome Component 2 (EXOSC2) Antibody, Abbexa, abx232902
EXOSC2 Antibody is a Mouse Monoclonal against EXOSC2.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Exosome Component 2 (EXOSC2) Antibody, Abbexa, abx232901
EXOSC2 Antibody is a Rabbit Polyclonal against EXOSC2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
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