Search results for Exostosin 1 (EXT1) Antibody
Exostosin 1 (EXT1) Antibody, Abbexa, abx029097
This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq].
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Exostosin 1 (EXT1) Antibody, Abbexa, abx001647
EXT1 Antibody is a Rabbit Polyclonal antibody against EXT1. Hereditary multiple exostoses (EXT) is an autosomal dominant disorder characterized by the formation of cartilage-capped tumors (exostoses) that develop from the growth plate of endochondral bone. This condition can lead to skeletal abnormalities, short stature and malignant transformation of exostoses to chondrosarcomas or osteosarcomas. Linkage analyses have identified three different genes for EXT, EXT1 on 8q24.1, EXT2 on 11p11-13 and EXT3 on 19p, a family of tumor suppressor genes. Most EXT cases have been attributed to missense or frameshift mutations, which lead to loss of function of the EXT genes. EXT1 is an ER-resident type II transmembrane glycoprotein and a heparan sulphate polymerase with both D-glucuronyl and N-acetyl-D-glucosaminoglycan transferase activities. Expression of EXT1 in cells results in the alteration of the synthesis and display of cell surface heparan sulfate glycosaminoglycans. EXT1 mutations have been identified in multiple types of human tumors.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Exostosin 1 (EXT1) Antibody, Abbexa, abx302428
EXT1 Antibody is a Rabbit Polyclonal against EXT1.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
Exostosin 1 (EXT1) Antibody (Biotin), Abbexa, abx314502
EXT1 Antibody (Biotin) is a Rabbit Polyclonal against EXT1 conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
Exostosin 1 (EXT1) Antibody (HRP), Abbexa, abx314500
EXT1 Antibody (HRP) is a Rabbit Polyclonal against EXT1 conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
Exostosin 1 (EXT1) Antibody (FITC), Abbexa, abx314501
EXT1 Antibody (FITC) is a Rabbit Polyclonal against EXT1 conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
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