Search results for F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody
F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody, Abbexa, abx026481
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. This protein is homologous to Xenopus bTrCP1, yeast Met30, Neurospora Scon2 and Drosophila Slimb proteins. It interacts with HIV-1 Vpu and connects CD4 to the proteolytic machinery. It also associates specifically with phosphorylated IkappaBalpha and beta-catenin destruction motifs, probably functioning in multiple transcriptional programs by activating the NF-kappaB pathway and inhibiting the beta-catenin pathway.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody, Abbexa, abx433611
F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody is a Goat Polyclonal against F-Box/WD Repeat-Containing Protein 1A (BTRC).
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB, IHC
Conjugation
Unconjugated
F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody, Abbexa, abx001393
BTRC Antibody is a Rabbit Polyclonal antibody against BTRC. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. The encoded protein mediates degradation of CD4 via its interaction with HIV-1 Vpu. It has also been shown to ubiquitinate phosphorylated NFKBIA (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha), targeting it for degradation and thus activating nuclear factor kappa-B. Alternatively spliced transcript variants have been described. A related pseudogene exists in chromosome 6.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IF/ICC
Conjugation
Unconjugated
F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody, Abbexa, abx122176
Rabbit Polyclonal against the BTRC protein.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody, Abbexa, abx302478
BTRC Antibody is a Rabbit Polyclonal against BTRC.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody (Biotin), Abbexa, abx315185
BTRC Antibody (Biotin) is a Rabbit Polyclonal against BTRC conjugated to Biotin.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
Biotin
F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody (FITC), Abbexa, abx315184
BTRC Antibody (FITC) is a Rabbit Polyclonal against BTRC conjugated to FITC.
Host
Rabbit
Reactivity
Human
Applications
Conjugation
FITC
F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody (HRP), Abbexa, abx315183
BTRC Antibody (HRP) is a Rabbit Polyclonal against BTRC conjugated to HRP.
Host
Rabbit
Reactivity
Human
Applications
ELISA
Conjugation
HRP
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