Search results for Feline Sarcoma Oncogene (FES) Antibody
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx002015
FES Antibody is a Rabbit Polyclonal antibody against FES. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx215463
Feline Sarcoma Oncogene (FES) Antibody is a Rabbit Polyclonal antibody for the detection of FES. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx015747
FES (feline sarcoma oncogene) and Fer are the only two members of a unique family of cytoplasmic protein tyrosine kinases.FES and Fer contain a central Src homology-2 (SH2) domain and a carboxy-terminal tyrosine kinase catalytic domain.They are structurally distinguished from other members of cytoplasmic protein tyrosine kinase subfamilies by the presence of amino-terminal Fer/CIP4 homology and coiled-coil domains.FES was originally identified as an oncogene from avian and feline retroviruses.Human c-Fes has been implicated in myeloid, vascular endothelial and neuronal cell differentiation.FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation.Mutations may activate the FES kinase and thereby contribute to cancer.However, recent data strongly suggests that the c-FES protein-tyrosine kinase is a tumor suppressor rather than a dominant oncogene in colorectal cancer.
Host
Mouse
Reactivity
Human
Applications
ELISA
Conjugation
Unconjugated
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx145934
FES Antibody is a Rabbit Polyclonal against FES.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx112510
Feline Sarcoma Oncogene Antibody is a Rabbit Polyclonal antibody against Feline Sarcoma Oncogene.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC
Conjugation
Unconjugated
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx129797
Feline Sarcoma Oncogene Antibody is a Rabbit Polyclonal against Feline Sarcoma Oncogene.
Host
Rabbit
Reactivity
Mouse
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx325863
FES Antibody is a Rabbit Polyclonal against FES.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx012141
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.
Host
Mouse
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx013365
Rabbit polyclonal antibody against FES protein. Immunogen region is Internal.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
Feline Sarcoma Oncogene (FES) Antibody, Abbexa, abx211566
FES Antibody is a Rabbit Polyclonal against FES.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, IHC
Conjugation
Unconjugated
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