Search results for G1/S-Specific Cyclin-D2 (CCND2) Antibody
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx034758
Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G (1) /S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G (1) phase. Hypophosphorylates RB1 in early G (1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB
Conjugation
Unconjugated
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx318068
CCND2 Antibody is a Rabbit Polyclonal against CCND2.
Host
Rabbit
Reactivity
Human, Mouse
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx001471
CCND2 Antibody is a Rabbit Polyclonal antibody against CCND2. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IF/ICC
Conjugation
Unconjugated
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx111853
Cyclin D2 (CCND2) Antibody is a Rabbit Polyclonal Antibody against Cyclin D2 (CCND2).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, IHC, IF/ICC
Conjugation
Unconjugated
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx034759
Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G (1) /S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G (1) phase. Hypophosphorylates RB1 in early G (1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
Host
Rabbit
Reactivity
Mouse
Applications
ELISA, WB
Conjugation
Unconjugated
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx232125
Cyclin D2 (CCND2) Antibody is a Rabbit Polyclonal against Cyclin D2 (CCND2).
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx455108
G1/S-Specific Cyclin-D2 (CCND2) Antibody is a Rabbit polyclonal antibody for the detection of Human G1/S-Specific Cyclin-D2 (CCND2).
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx339094
CCND2 Antibody is a Rabbit Polyclonal against CCND2.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx328472
CCND2 Antibody is a Rabbit Polyclonal against CCND2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
G1/S-Specific Cyclin-D2 (CCND2) Antibody, Abbexa, abx171974
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. Cyclin D2 (CCND2) Antibody is a Mouse Monoclonal antibody against Cyclin D2 (CCND2).
Host
Mouse
Reactivity
Human
Applications
WB, IHC, IF/ICC
Conjugation
Unconjugated
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