Search results for G1/S-Specific Cyclin-E1 (CCNE1) Antibody

Showing 1 – 10 of4products
G1/S-Specific Cyclin-E1 (CCNE1) Antibody Brand Logo
ID: BAB080463412

G1/S-Specific Cyclin-E1 (CCNE1) Antibody, Abbexa, abx224072

CCNE1 Antibody is a Mouse Monoclonal against CCNE1.

Host

Mouse

Reactivity

Human, Mouse

Applications

ELISA, FCM

Conjugation

G1/S-specific cyclin-E1 (CCNE1) Antibody Brand Logo
ID: BAB494665879

G1/S-specific cyclin-E1 (CCNE1) Antibody, Abbexa, abx402561

G1/S-specific cyclin-E1 (CCNE1) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human CCNE1.

Host

Rabbit

Reactivity

Human

Applications

ELISA, IHC, IF/ICC

Conjugation

Unconjugated

G1/S-specific cyclin-E1 (CCNE1) Antibody Brand Logo
ID: BAB097912734

G1/S-specific cyclin-E1 (CCNE1) Antibody, Abbexa, abx402098

G1/S-specific cyclin-E1 (CCNE1) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human CCNE1.

Host

Rabbit

Reactivity

Human

Applications

ELISA, IF/ICC

Conjugation

Unconjugated

G1/S-Specific Cyclin-E1 (CCNE1) Antibody Brand Logo
ID: BAB073168295

G1/S-Specific Cyclin-E1 (CCNE1) Antibody, Abbexa, abx032766

Cyclin E1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin E1 forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E1 accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of Cyclin E1 has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB.

Host

Rabbit

Reactivity

Human

Applications

ELISA, WB, IHC, FCM

Conjugation

Unconjugated

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