Search results for HIF-1 alpha antibody

HIF-1 alpha antibody, Covalab, Ref 00029025

Anti-HIF-1 alpha antibody, Abcam, AB114977

What is this antibody validated in? Anti-HIF-1 alpha antibody (ab114977) is a rabbit polyclonal antibody and is validated for use in Immunohistochemistry (IHC-P) in Human, Mouse samples. Trusted by the scientific community Anti-HIF-1 alpha (ab114977) was first used in a scientific publication in 2011 and has been cited over 20 times in peer-reviewed journals.

Anti-HIF-1 alpha antibody, Abcam, AB216842

HIF-1 alpha Antibody#3716, Cell Signaling Technology (CST), 3716

HIF-1 alpha Antibody detects endogenous levels of total HIF-1α protein. This antibody does not cross-react with other family members at physiological conditions, and does not detect significant levels of hydroxylated HIF-1α.

Anti-HIF-1 alpha antibody [EP1215Y], Abcam, AB51608

Anti-HIF-1 alpha antibody [EP1215Y] (ab51608) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ChIC/CUT&RUN-seq, Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB in human samples. Anti-HIF-1 alpha antibody [EP1215Y] (ab51608) has been cited over 340 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-HIF-1 alpha antibody [EP1215Y] (ab51608) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-HIF-1 alpha antibody [EP1215Y] (ab51608) has been confirmed by testing in knockout samples. Anti-HIF-1 alpha antibody [EP1215Y] (ab51608) has 12 independent reviews from customers. Anti-HIF-1 alpha antibody [EP1215Y] (ab51608) specifically detects HIF-1 alpha (UniProt ID: Q16665; Molecular weight: 93kDa) and is sold in 100 uL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EP1215Y - ab2173 . Antibody clone EP1215Y is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647 ( ab19569 ). HIF-1 alpha, also known as hypoxia-inducible factor 1-alpha (HIF1A), is a critical regulator of cellular response to low oxygen levels. HIF1A is a transcription factor commonly referred to as a "master regulator of the hypoxic response" for its central role in the regulation of cellular adaptations to hypoxia. Hypoxia contributes to the pathophysiology of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. A highly specific HIF-1 alpha antibody, essential for studying hypoxia-inducible factors and oxygen homeostasis. This antibody is crucial in tumor hypoxia research, particularly in understanding cancer progression and angiogenesis. It is widely used in studies of metastasis and HIF-1 alpha inhibitors. The HIF1A molecular weight is approximately 120 kDa, and detecting it accurately is essential for understanding its role in the tumor microenvironment. Elevated HIF-1 alpha levels are linked to tumor progression, angiogenesis, and metastasis. Monitoring HIF-1 alpha can provide valuable insights into cancer biology and potential therapeutic targets. This antibody is also validated for CUT&RUN-seq, which is a key application to map protein-DNA interactions on a genome-wide scale using NGS. For Mouse specific Hif-1-alpha rabbit monoclonal antibody, please see ab179483 (clone ID: EPR16897). ab179483 has been confirmed for Mouse sample in WB. We have mixed customer feedback towards the rat specificity so we are unable to confirm and guarantee its performance with rat samples. Please contact technical team for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Anti-HIF-1 alpha antibody [EPR16897], Abcam, AB179483

Anti-HIF-1 alpha antibody [EPR16897] (ab179483) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ChIC/CUT&RUN-seq, ChIP,-seq ICC/IF, IP and WB. First used in a scientific publication in 2016, it is highly cited in over 190 times in peer reviewed journals. Abcam's high quality manufacturing and validation processes ensure Anti-HIF-1 alpha antibody [EPR16897] (ab179483) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Validated for both CUT&RUN and ChIP-seq, which are key applications to map protein-DNA interactions on a genome-wide scale using NGS. The specificity of Anti-HIF-1 alpha antibody [EPR16897] (ab179483) has been confirmed by Western Blot testing in HIF-1 alpha knockout HAP1 cells making its performance in human, mouse and rat samples trusted by the scientific community. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) has 5 independent reviews from customers. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) specifically detects HIF-1 alpha (UniProt ID: Q16665; Molecular weight: 93kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR16897 - Anti-HIF-1 alpha antibody [EPR16897] - BSA and Azide freeab221610. Antibody clone EPR16897 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647 ( ab208419 , ab208420 ). HIF-1 or hypoxia inducible factor 1, is a transcription factor commonly referred to as a ""master regulator of the hypoxic response"" for its central role in the regulation of cellular adaptations to hypoxia. Hypoxia contributes to the pathophysiology of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. A highly specific HIF-1 alpha antibody, essential for studying hypoxia-inducible factors and oxygen homeostasis. This antibody is crucial in tumor hypoxia research, particularly in understanding cancer progression and angiogenesis. It is widely used in studies of metastasis and HIF-1 alpha inhibitors. Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Anti-HIF-1 alpha antibody [ESEE122], Abcam, AB8366

Under normoxic conditions HIF-1 alpha has a short half-life. It is largely undetectable in cells or tissues grown under normoxic conditions. It is stabilized only at O 2 concentrations below 5% and upon stabilization under hypoxic conditions HIF-1 translocates to the nucleus. Therefore we recommend western blots using nuclear extracts and running Hypoxia treated samples as positive control ( ab180880 ). Hypoxia can be induced with treatment using certain agents e.g. CoCl 2 or DFO, etc. so proper sample preparation is critical. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Anti-HIF-1 alpha antibody [H1alpha67], Abcam, AB1

Anti-HIF-1 alpha antibody [H1alpha67] (ab1) is a House Mouse Monoclonal antibody and is validated for use in Flow Cyt (Intra), ICC/IF, IP, WB. Anti-HIF-1 alpha antibody [H1alpha67] (ab1) has been cited over 343 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality validation processes ensure Anti-HIF-1 alpha antibody [H1alpha67] (ab1) has high sensitivity and specificity. The specificity of Anti-HIF-1 alpha antibody [H1alpha67] (ab1) has been confirmed by testing in knockout samples. Anti-HIF-1 alpha antibody [H1alpha67] (ab1) has 41 independent reviews from customers. Anti-HIF-1 alpha antibody [H1alpha67] (ab1) specifically detects HIF-1 alpha (UniProt ID: Q16665; Molecular weight: 93kDa) and is sold in 100 ug selling sizes. Antibody clone H1alpha67 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647 ( ab23848 ). HIF-1 alpha, also known as hypoxia-inducible factor 1-alpha (HIF1A), is a critical regulator of cellular response to low oxygen levels. HIF1A is a transcription factor commonly referred to as a "master regulator of the hypoxic response" for its central role in the regulation of cellular adaptations to hypoxia. Hypoxia contributes to the pathophysiology of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. A highly specific HIF-1 alpha antibody, essential for studying hypoxia-inducible factors and oxygen homeostasis. This antibody is crucial in tumor hypoxia research, particularly in understanding cancer progression and angiogenesis. It is widely used in studies of metastasis and HIF-1 alpha inhibitors. The HIF1A molecular weight is approximately 120 kDa, and detecting it accurately is essential for understanding its role in the tumor microenvironment. Elevated HIF-1 alpha levels are linked to tumor progression, angiogenesis, and metastasis. Monitoring HIF-1 alpha can provide valuable insights into cancer biology and potential therapeutic targets. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Anti-HIF-1 alpha antibody [mgc3], Abcam, AB16066

What is this antibody validated in? Anti-HIF-1 alpha antibody [mgc3] (ab16066) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of HIF-1 alpha? Anti-HIF-1 alpha [mgc3] (ab16066) specifically detects a band for HIF-1 alpha (UniProt: Q16665) at a molecular weight of 92kDa. Trusted by the scientific community Anti-HIF-1 alpha [mgc3] (ab16066) was first used in a scientific publication in 2004 and has been cited over 140 times in peer-reviewed journals. Reviewed by scientists Anti-HIF-1 alpha [mgc3] (ab16066) has over 10 independent reviews from customers.

Anti-HIF-1 alpha antibody [RM1116], Abcam, AB317044

What are recombinant multiclonals? Recombinant multiclonals are a mixture of recombinant antibodies co-expressed from a library of heavy and light chains. They offer several advantages including: - The sensitivity of polyclonal antibodies by recognising multiple epitopes - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production View our range of recombinant multiclonal antibodies . Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .