Search results for Hk2 antibody

Hk2 antibody, Genetex, GTX124375

Hexokinase-2 (HK2) Antibody, Abbexa, abx137285

Hexokinase-2 (HK2) Antibody is a Mouse Monoclonal antibody against Hexokinase-2 (HK2).

Hexokinase-2 (HK2) Antibody, Abbexa, abx455525

Hexokinase-2 (HK2) Antibody is a Rabbit polyclonal antibody for the detection of Human Hexokinase-2 (HK2).

Hexokinase 2 (HK2) Antibody, Abbexa, abx128624

Hexokinase 2 Antibody is a Rabbit Polyclonal against Hexokinase 2.

Hexokinase 2 (HK2) Antibody, Abbexa, abx000947

HK2 Antibody is a Rabbit Polyclonal antibody against HK2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Hexokinase-2 (HK2) Antibody, Abbexa, abx233848

Hexokinase 2 Antibody is a Rabbit Polyclonal against Hexokinase 2.

Hexokinase 2 (HK2) Antibody, Abbexa, abx033901

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase activity is involved in the first step in several metabolic pathways. HK3 is bound to the outer mitochondrial membrane. Its hydrophobic N-terminal sequence may be involved in membrane bindng. It is the predominant hexokinase isozyme expressed in insuline-responsive tissues such as skeletal muscle. The N and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.

Hexokinase 2 (HK2) Antibody, Abbexa, abx100804

Polyclonal Antibody to Hexokinase 2 (HK2).

Hexokinase 2 (HK2) Antibody, Abbexa, abx011658

The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases.Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Hexokinase 2 (HK2) Antibody, Abbexa, abx214587

HK2 Antibody is a Rabbit Polyclonal against HK2.