Search results for Homeobox protein NANOG
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx433010
NANOG Antibody is a Goat Polyclonal antibody against NANOG.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB, IHC
Conjugation
Unconjugated
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx137438
NANOG Antibody is a Mouse against Human. NANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IHC
Conjugation
Unconjugated
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx028376
NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cell proliferation and self-renewal. It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. NANOG acts as a transcriptional activator or repressor. It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, this protein promotes cells to enter into S phase and proliferation.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IHC, IF/ICC, FCM
Conjugation
Unconjugated
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx341136
Homeobox Protein NANOG (NANOG) Antibody is a Mouse Monoclonal antibody for the detection of Human, Mouse, Rat NANOG.
Host
Mouse
Reactivity
Human, Mouse, Rat
Applications
ELISA, WB, IF/ICC, FCM
Conjugation
Unconjugated
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx349975
Homeobox Protein NANOG (NANOG) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human NANOG.
Host
Rabbit
Reactivity
Human
Applications
ELISA, FCM
Conjugation
Unconjugated
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx432151
NANOG Antibody is a Goat Polyclonal antibody against NANOG.
Host
Goat
Reactivity
Human
Applications
P-ELISA, WB, IHC, IF/ICC
Conjugation
Unconjugated
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx019137
NANOG Antibody is a Rabbit Polyclonal antibody against Human and Mouse.
Host
Rabbit
Reactivity
Human, Mouse
Applications
WB
Conjugation
Unconjugated
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx114023
Nanog Homeobox Antibody is a Rabbit Polyclonal antibody against Nanog Homeobox.
Host
Rabbit
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx011232
NANOG: Nanog homeobox. Entrez Protein NP079141. Nanog is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells. Nanog mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells. Human Nanog protein shares 52% overall amino acid identity with the mouse protein and 85% identity in the homeodomain. Human Nanog maps to gene locus 12p13.31, whereas mouse Nanog maps to gene loci 6 F2. Murine embryonic Nanog expression is detected in the inner cell mass of the blastocyst. High levels of human Nanog expression were detected by Northern analysis in the undifferentiated N-Tera embryonal carcinoma cell line.
Host
Mouse
Reactivity
Human
Applications
ELISA, WB, IF/ICC
Conjugation
Unconjugated
Homeobox Protein NANOG (NANOG) Antibody, Abbexa, abx432150
Nanog Antibody is a Goat Polyclonal antibody against Nanog.
Host
Goat
Reactivity
Mouse
Applications
P-ELISA, WB
Conjugation
Unconjugated
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