Search results for Human Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody Pair

Human Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody Pair, Abbexa, abx378397

Human Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody Pair for use in Sandwich ELISA assay development. This antibody pair contains: Component Quantity Capture Antibody 100 µg Biotin-Conjugated Detection Antibody 50 µl The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta is also a ligand for CCR1 and CCR2 isoform B.