Search results for IRAK1 (pS376) Antibody

IRAK1 (pS376) Antibody, Abbexa, abx332851
IRAK1 (pS376) Antibody is a Rabbit Polyclonal against IRAK1 (pS376).
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated

IRAK1 (pS376) Antibody, Abbexa, abx031872
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. IRAK1 binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Isoform 1 binds rapidly but is then degraded allowing isoform 2 to mediate a slower, more sustained response to the cytokine. Isoform 2 is inactive suggesting that the kinase activity of this enzyme is not required for IL-1 signaling. Once phosphorylated, IRAK1 recruits the adapter protein PELI1. This protein is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.
Host
Rabbit
Reactivity
Human
Applications
ELISA, IF/ICC, DB
Conjugation
Unconjugated

Interleukin 1 Receptor Associated Kinase 1 Phospho-Ser376 (IRAK1 pS376) Antibody, Abbexa, abx323073
IRAK1 (pS376) Antibody is a Rabbit Polyclonal against IRAK1 (pS376).
Host
Rabbit
Reactivity
Human
Applications
ELISA, IHC
Conjugation
Unconjugated
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